abstract：:Multiple retrograde fluorescent tracing was employed to investigate the organization of the rat entopeduncular nucleus projections to the lateral habenula, ventral anterior-ventral lateral thalamus, parafasicular-centre median complex, and tegmenti pedunculopontis area of the brain stem. The results indicate that neur...

journal_title：Brain research

authors： van der Kooy D,Carter DA

更新日期：1981-04-27 00:00:00

abstract：:The opioid peptides Leu-enkephalin, Met-enkephalin and D-Ala2-Met-enkephalinamide were injected at various concentrations into the neocortex and hippocampus of rats to examine their effects on EEG activity and DC potentials. All three compounds were found to elicit spreading depression (SD) in both structures. Higher ...

journal_title：Brain research

authors： Sprick U,Oitzl MS,Ornstein K,Huston JP

更新日期：1981-04-06 00:00:00

abstract：:Spectrally opponent processes of ON-type retinal ganglion cells and the blue preference behavior were identified by parallel physiological and behavioral experiments in Rana pipiens. Spectral opponency of retinal ON-units was measured by recording from optic nerve terminals in the anterior thalamus, while the retina w...

journal_title：Brain research

authors： Kicliter E,Kay CJ,Chino YM

更新日期：1981-04-06 00:00:00

abstract：:The ability of embryonic hippocampal tissue to promote regeneration of cholinergic axons in the septohippocampal system has been studied in adult rats. Strips of embryonic hippocampus, taken from 7-40 mm rat fetuses, were implanted into a 2-3 mm wide cavity which completely transected the septal cholinergic axons inne...

journal_title：Brain research

authors： Kromer LF,Björklund A,Stenevi U

更新日期：1981-04-06 00:00:00

abstract：:We examined the effects of early epileptiform activity on development of visuocortical receptive fields in the rabbit. Aqueous penicillin was injected twice a day into a cannula implanted over the monocular area of one visual cortex. Drug administration was begun on postnatal day 8-9 and continued until postnatal day ...

journal_title：Brain research

authors： Crabtree JW,Chow KL,Ostrach LH,Baumbach HD

更新日期：1981-04-01 00:00:00

abstract：:Nerve cell dissociated from the cerebral cortex of mice were co-cultured with isolated pancreatic islets of Langerhans. After two weeks of co-culture, numerous axons had invaded the islets and differentiated nerve endings were closely juxtaposed to the endocrine islet cells. In contrast, no remnants of nerve cells wer...

journal_title：Brain research

authors： Hooghe-Peters EL,Meda P,Orci L

更新日期：1981-04-01 00:00:00

abstract：:The development of brain stem reticular core neurons in prenatally undernourished rats was investigated using the Golgi technique to determine the effect of immediate postnatal nutritional rehabilitation. Quantitative measurements of dendritic extent of branching and of cell size were compared in experimental and cont...

journal_title：Brain research

authors： Hammer RP Jr,van Marthens E

更新日期：1981-04-01 00:00:00

abstract：:Work with ion-selective microelectrodes on the retina of the honeybee drone has shown that potassium is released from photoreceptors during activity and enters glial cells. Measurements of the extracellular voltage gradients indicate that, in this preparation, currents flowing through the glial cells in the 'spatial b...

journal_title：Brain research

authors： Gardner-Medwin AR,Coles JA,Tsacopoulos M

更新日期：1981-03-30 00:00:00

abstract：:Partial, unilateral olfactory nerve section was performed in mice, and the behavior of the olfactory marker protein (OMP) studied, after this experimental manipulation, with the peroxidase--antiperoxidase method. The protein, which in normal mice is present only in mature olfactory sensory neurons, after unilateral le...

journal_title：Brain research

authors： Monti Graziadei GA,Graziadei PP

更新日期：1981-03-30 00:00:00

abstract：:Medium conditioned by NG108-15 neuroblastoma x glioma hybrid cells contains a factor which increases the number of acetylcholine receptor (AChR) aggregates on cultured myotubes. Protease digestion indicates that the AChR aggregation factor is a protein, and the molecular weight is from 150,000 to 250,000 daltons as es...

journal_title：Brain research

authors： Bauer HC,Daniels MP,Pudimat PA,Jacques L,Sugiyama H,Christian CN

更新日期：1981-03-30 00:00:00

abstract：:A monospecific antibody against tyrosine hydroxylase (TH), purified from a transplantable rat pheochromocytoma, was produced in rabbits. Immunohistochemical techniques were employed in order to determine if a relationship exists between the subcellular distribution of TH and the level of activation of the enzyme in th...

journal_title：Brain research

authors： Stephens JK,Masserano JM,Vulliet PR,Weiner N,Nakane PK

更新日期：1981-03-30 00:00:00

abstract：:The anesthetic-sedative barbiturate pentobarbital (PB) and the anticonvulsant barbiturate phenobarbital (PhB) were applied to mammalian spinal cord neurons in primary dissociated cell culture to assess their effects on: (1) postsynaptic GABA-responses; (2) paroxysmal activity produced by the convulsant bicuculline; (3...

journal_title：Brain research

authors： Schulz DW,Macdonald RL

更新日期：1981-03-23 00:00:00

abstract：:Perfusion of artificial CSF from a lateral ventricle to the cerebral cortical subarachnoid space in anaesthetized cats was used to study the contribution of the cerebral cortex to the concentration of 5-hydroxyindoleacetic acid (5-HIAA) in CSF. The technique did not cause rupture of the meninges. The use of [14C]5-HIA...

journal_title：Brain research

authors： Min-Chu L,Mackenna BR,Watt JA

更新日期：1981-03-23 00:00:00

abstract：:Previous work has shown that bilateral injection of as little as 10 microgram of cycloheximide (CHX) into the amygdala, but not into the internal capsule, caused a time-dependent disruption of long-term retention of passive avoidance training. Under these conditions, protein synthesis in the entire brain was inhibited...

journal_title：Brain research

authors： Kesner RP,Partlow LM,Bush LG,Berman RF

更新日期：1981-03-23 00:00:00

abstract：:The influence of the cortico-geniculate pathway on identified X and Y lateral geniculate cells was studied by reversibly cooling visual cortical areas 17 and 18. The majority (86.5%) of cells changed their response to visual stimulation when cortex was inactivated, and both X- and Y-cells were modulated by the cortica...

journal_title：Brain research

authors： Geisert EE,Langsetmo A,Spear PD

更新日期：1981-03-16 00:00:00

abstract：:Discrete axon-sparing lesions were placed unilaterally in the mesencephalon by the local injection of kainic acid. Unilateral lesions of the dorsal reticular formation just beneath the superior colliculus and lateral to the periacqueductal grey resulted in consistent ipsiversive apomorphine-induced circling. Only weak...

journal_title：Brain research

authors： Mulas A,Longoni R,Spina L,Del Fiacco M,Di Chiara G

更新日期：1981-03-16 00:00:00

abstract：:Monoclonal antibodies were produced against tyrosine hydroxylase (TH), the enzyme catalyzing the rate limiting step in catecholamine neurotransmitter synthesis. An enzyme linked immunosorbant assay was used to detect the presence of specific antibody in culture. Specificity of the antibodies is characterized. These mo...

journal_title：Brain research

authors： Ross ME,Reis DJ,Joh TH

更新日期：1981-03-16 00:00:00

abstract：:Two distinct serotonin receptors in mammalian brain are labeled respectively with [3H]serotonin (5-HT1) and [3H]spiperone (5-HT2). In general agonists display highest affinities for 5-HT1 while antagonists prefer 5-HT2 sites. To conduct regional studies of 5-HT receptors, we estimated 5-HT2 sites with [3H]spiperone, u...

journal_title：Brain research

authors： Peroutka SJ,Snyder SH

更新日期：1981-03-16 00:00:00

abstract：:The structure of the plasma membrane of two neuronal cell types was quantitatively assessed in freeze-fracture replicas of rat cerebellar cortex from 2 to 73 postnatal days. The measurement of the number and size of intramembrane particles (IMP) in different regions of the Purkinje cells and of the granule cell showed...

journal_title：Brain research

authors： Garcia-Segura LM,Perrelet A

更新日期：1981-03-09 00:00:00

abstract：:Measurement of histamine and its metabolizing enzymes in a variety of chordate species indicated that histamine and histamine methyltransferase were present in brain of all vertebrate species with a recognizable brain structure. Diamine oxidase was absent in mammalian brain but was present in brain of lower vertebrate...

journal_title：Brain research

authors： Almeida AP,Beaven MA

更新日期：1981-03-09 00:00:00

abstract：:Immunohistochemical localization of the decapeptide gonadotropin releasing hormone (GnRH) in neural structures in the pony brain and infundibulum (INF) was conducted at the light-microscopic level. This procedure utilized an antiserum generated against GnRH conjugated to bovine serum albumin. In the rostral INF, GnRH ...

journal_title：Brain research

authors： Dees WL,Sorensen AM Jr,Kemp WM,McArthur NH

更新日期：1981-03-09 00:00:00

abstract：:The actions of pentobarbital (PB) and diphenylhydantoin (DPH) have been studied on neurons of dorsal root ganglia from adult rats. At anesthetic level (i.e. 1--2 x 10(-4) M), PB greatly enhanced neuronal responses to gamma-aminobutyric acid (GABA); at 10(-3) M PB caused a small depolarization and profoundly attenuated...

journal_title：Brain research

authors： Connors BW

更新日期：1981-03-02 00:00:00

abstract：:The involvement of the nucleus intercollicularis (ICo) region of the midbrain, an estrogen-sensitive area, in the expression of estrogen-dependent female courtship behavior was examined with radiofrequency lesion and intracranial hormone implant techniques. Bilateral lesions in the ICo region caused a reduction in the...

journal_title：Brain research

authors： Cohen J,Cheng MF

更新日期：1981-03-02 00:00:00

abstract：:GABA levels, high affinity GABA uptake and glutamic acid decarboxylase levels are reduced in rat ventroanterolateral thalamic nucleus after destruction of the entopeduncular nucleus with kainic acid. This is strong evidence that GABA is an entopedunculothalamic neurotransmitter. The striatoentopeduncular pathway is al...

journal_title：Brain research

authors： Penney JB Jr,Young AB

更新日期：1981-02-23 00:00:00

abstract：:Cell bodies and dendrites of neurones in the thalamic reticular nucleus projecting to the dorsal lateral geniculate nucleus in adult albino rats, were labelled by retrograde transport of horseradish peroxidase (HRP). In the same animals the terminals of cortico-reticular axons were made identifiable by ipsilateral vis...

journal_title：Brain research

authors： Ohara PT,Lieberman AR

更新日期：1981-02-23 00:00:00

abstract：:Neurotensin is a putative peptide neurotransmitter in the mammalian brain. The light microscopic localization of the neurotensin receptor has been carried out by the autoradiographic localization of [3H]neurotensin binding sites in slide-mounted tissue sections. Large variations in receptor distribution were found, ev...

journal_title：Brain research

authors： Young WS 3rd,Kuhar MJ

更新日期：1981-02-16 00:00:00

abstract：:The effects of the possible metabolites of taurine--taurocyamine and hypotaurine--and of homotaurine on spike discharge frequency of guinea pig cerebellar Purkinje cells were investigated in comparison with taurine and GABA. Taurocyamine, hypotaurine and homotaurine all dose-dependently suppressed the spike frequency ...

journal_title：Brain research

authors： Okamoto K,Sakai Y

更新日期：1981-02-16 00:00:00

abstract：:The ionic basis of norepinephrine (NE) action was studied with intracellular recording techniques in the rat hippocampal slice. Topical application of NE caused, in CA1 neurons, a 3-4 mV hyperpolarization associated with a 10-20% decrease in input resistance. This effect was accompanied by a decrease in spontaneous ac...

journal_title：Brain research

authors： Segal M

更新日期：1981-02-09 00:00:00

abstract：:We have recently reported the existence within chick embryo heart cell conditioned medium (HCM) of two distinct and independently assayable factors. One agent, ciliary neuronotrophic factor (CNTF), supports the in vitro survival of 8-day chick embryo ciliary ganglionic (CG) neurons. The other factor, polyornithine-att...

journal_title：Brain research

authors： Adler R,Manthorpe M,Skaper SD,Varon S

更新日期：1981-02-09 00:00:00

abstract：:Hypothalamic control of thermoregulatory evaporation has been examined in hydrated and dehydrated cats exposed to warm ambient temperatures. Reduction in evaporative cooling during dehydration is associated with increased hypothalamic temperature. Local thermal stimulation of the hypothalamus indicates that the thermo...

journal_title：Brain research

authors： Doris PA,Baker MA

更新日期：1981-02-09 00:00:00

abstract：:The possibility of retinotopic organization of pathways of retinal fibers within the optic tract and the tectum of the frog was studied by selective labeling of the retinal fibers with horseradish peroxidase. Within the optic tract the pathways of the ventral, temporal and dorsal retinal fibers were ordered from the d...

journal_title：Brain research

authors： Fujisawa H,Watanabe K,Tani N,Ibata Y

更新日期：1981-02-09 00:00:00

abstract：:Rabbits passively oscillated in the horizontal plane with a free hand tended to stabilize their head in space (re: earth-fixed surroundings) by moving the head on the trunk (neck angular deviation, NAD) opposite the passively imposed body rotation. The gain (NAD/body rotation) of head stabilization varied from 0.0 to ...

journal_title：Brain research

authors： Fuller JH

更新日期：1981-02-02 00:00:00

abstract：:The development from primary to augmenting responses of somatosensory (SI) cortical area to low-frequency stimulation of the ventrobasal (VB) thalamus or white matter (WM) beneath SI in VB-lesioned preparations was studied by field potential analysis and extracellular unit recording. Compared to the major postsynaptic...

journal_title：Brain research

authors： Morin D,Steriade M

更新日期：1981-01-26 00:00:00

abstract：:Axonal projections of medial brain stem areas rich in serotonin-containing neurons were identified in layers I and II of cat medullary dorsal horn using EM autoradiography. Following [3H]amino acid injections into the brain stem, labeled axonal endings were found throughout layers I and II but were most numerous in la...

journal_title：Brain research

authors： Ruda MA,Allen B,Gobel S

更新日期：1981-01-26 00:00:00

abstract：:Of 602 rats tested for amphetamine-induced or nocturnal rotation (circling behavior), 54.8% (P less than 0.025) had right side biases. Of 292 rats tested in two-lever operant situations, 57.5% (P less than 0.02) preferred the right lever. Right-biased rats were significantly more active and had stronger side preferenc...

journal_title：Brain research

authors： Glick SD,Ross DA

更新日期：1981-01-26 00:00:00

abstract：:The distribution of fast axonally transported proteins was studied by electron microscope radioautography in ciliary ganglia of chickens treated or not treated with acrylamide. At 3 h after the intracerebral injection of [3H]lysine, the preganglionic axons of the untreated chickens displayed few silver grains, mainly ...

journal_title：Brain research

authors： Chretien M,Patey G,Souyri F,Droz B

更新日期：1981-01-26 00:00:00

abstract：:In this study, noradrenergic (NE) terminals in the dorsal raphe were identified by [3H]NE electron microscopic (EM) autoradiography. Lesioning of NE terminals by treatment with the selective catecholamine neurotoxin, 6-hydroxydopamine produced a marked decrease in NE-labelled terminals. [3H]5-HT EM autoradiography of ...

journal_title：Brain research

authors： Baraban JM,Aghajanian GK

更新日期：1981-01-05 00:00:00

abstract：:Experiments were performed which demonstrate that low power, pulsed microwave exposure induces a significant increase in local cerebral blood flow within the brain of the conscious rat. Previous studies purporting to examine changes in brain vascular permeability induced by microwave radiation must be re-evaluated in ...

journal_title：Brain research

authors： Oscar KJ,Gruenau SP,Folker MT,Rapoport SI

更新日期：1981-01-05 00:00:00

abstract：:The postnasal development of the Na-independent [3H]glutamate binding sites, which exhibit some characteristics of postsynaptic glutamate receptors, has been studied in rat hippocampal membranes. The amount of binding sites (expressed in pmol/hippocampus) represents 4% of the adult level at postnatal day (PND) 4, incr...

journal_title：Brain research

authors： Baudry M,Arst D,Oliver M,Lynch G

更新日期：1981-01-01 00:00:00

abstract：:Rabbits reared from birth in stroboscopic illumination have no experience of visual motion. In primary visual cortex of these animals there is a large reduction in the number of cells which are direction selective. This result, contrary to previous reports, shows that the rabbit visual system can be modified by early ...

journal_title：Brain research

authors： Pearson HE,Berman N,Murphy EH

更新日期：1981-01-01 00:00:00